Cruise from Los Angeles or Miami and pick the trips that make your favourite stops. Prefer more of Mexico? There's a cruise with stops in Manzanillo, Puerto Vallarta and Cabo San Lucas. Want to include some Caribbean islands? Finish your cruise in Puerto Rico or stop in Grand Cayman.
From Cartagena to Cabo San Lucas, cruise the Panama Canal
We've circled the globe and couldn't find any sailings that match your search. View All Cruises
We're having trouble retrieving these cruises. View All Results
Stopping at different cruise ports during a Panama Canal crossing makes it easy to savour the varied flavours of these countries, each with its own signature spice and tang.
A cruise to the Panama Canal is a chance to land on amazing destinations during the same trip. Get in some beach time Oranjestad, Aruba. See traditional tapestry-making in Huatulco, Mexico. Or go snorkelling along the coral reef off the coast of Grand Cayman.