14 Night Mediterranean Cities

As the capital of Spain’s Andalusia region, the energetic city of Seville stands tall at the banks of the Guadalquivir River. And like its rich flamenco legacy, this well-preserved city performs an elaborate dance between Moorish history and youth-infused street culture. A jovial spirit and intoxicating personality flow freely throughout its narrow streets, from Old Town’s palaces to the tapas bars of Santa Cruz. Admire the lavish stylings of Plaza de España from a painted ceramic bench, or stroll through Maria Luisa Park’s serene greenery. Stand in Spain’s oldest bullring at the Bullfighting Museum— or breathe in citywide views from the top of Torre del Oro.

Cagliari, the capital of the Italian island of Sardinia, is situated high upon hills that offer a panoramic view of the Golfo degli Angeli — the Gulf of Angels. Walk along Poetto beach, with its soft sand and clear water, or visit the urban park of Molentargius with its flamingos, wetlands and magnificent birds. Cruise to Sardinia, Italy to peruse the local architectural sites: See Bastione di Saint Remy with its breathtaking terrace and Torre dell'Elefante, a medieval tower with a 360-degree view of the city. And don't forget to take a meditative stroll through the lavish interior of the 13th-century Cagliari Cathedral.

With 28 centuries of celebrated history, Rome holds the edge when it comes to unrivaled adventures. The city that sparked the world’s largest empire is very much alive today with a jumble of ancient ruins, world-renowned art and vivacious street culture. Here you can live la dolce vita, recalling the glory days of Ancient Rome and twirling forks full of pasta in a trattoria. Ride past centuries-old basilicas in a three-wheeled Ape Calessino, or stand in awe of paintings by Italian masters at Villa Borghese. Whether it’s Vatican City’s spiritual allure, Trastevere’s backstreet charms, or the Colosseum’s embattled legacy— The Eternal City endures with endless adventures.

It’s easy to see why Barcelona is the most-visited city in Spain. As the capital of the country’s Catalonia region, this cityscape’s cultural mosaic pieces together a 2,000-year-old hodgepodge of sun-drenched beaches, cutting edge architecture, and a world-renowned dining and drinking scene. Catalan architect Antoni Gaudí left his modernist handprint all over the city, while medieval treasures linger in historic Gothic Quarter squares. Get lost in the whimsical gardens of Park Güell or savor a chef-led Catalan cooking class. Browse art collections dedicated to Picasso and Miro— or ride a cable car to the top of Montjuïc Hill, relishing citywide views along the way.

Lisbon is a quintessential European city, full of natural beauty, historic architecture and culinary pleasures — not to mention one of the best climates anywhere on the planet. To get to know Portugal's capital, walk between the captivating miradouros — terrace viewpoints that are scattered on the hilltops, offering stunning vistas from the sea to the castles and beyond. Watch as the light peeks through the clouds and shines down on The City of Seven Hills during your cruise to Lisbon. If you're a history buff, head to Belem or nearby Sintra to explore UNESCO World Heritage Sites like the Jeronimos Monastery and Quinta da Regalaira.

The sun will shine upon you as you enter the harbor of Vigo, the largest city in Spain's autonomous Galicia region. Start your adventure by ascending the Castro Fortress — you can take in views of the city and the lushly forested mountains around it from these granite-walled 17th-century fortifications. Then, learn up about the region at one of Vigo's excellent museums: Museo do Mar Galicia features exhibits on the local oceanography and ecosystems, while the Vigo Museum of Contemporary Art hosts a changing lineup of participatory workshops and installations by innovative artists working today. Later, stretch your legs on the GR-53, a 25-mile path along the coastline and low mountain peaks around the city, or relax by the blue waters of Cies Beach.