Top Eastern Mediterranean Cruises: Greece, Turkey and Israel

Cruise to These Memorable Mediterranean Destinations and Attractions

By Cassie Bailey | Published: February 4, 2021 | Updated: Februrary 11, 2026

Embark on a voyage to remember on a cruise to the Eastern Mediterranean. Set foot ashore at Istanbul, Ephesus (Kuşadası), Rhodes, Santorini, Jerusalem (Ashdod) and Haifa. Here is a top 26 list of the best attractions and tours for a Greece, Turkey or Israel vacation. Enjoy as many Eastern Mediterranean Cruises as your adventurous spirit will allow!

Key Takeaways

● Explore historic cities and ancient ruins across Turkey, Greece and Israel, from Istanbul’s mosques to Ephesus and Jerusalem’s sacred sites.

● The Eastern Mediterranean boasts breathtaking natural landscapes, including Santorini’s cliffs, volcanic islands and Pamukkale’s surreal terraces.

● You’ll experience iconic cultural highlights, like the Grand Bazaar, Topkapı Palace, Lindos Acropolis and the Church of the Holy Sepulchre.

● You can also discover iconic cultural highlights on unforgettable Mediterranean cruise experiences that you can enjoy with family, friends and even the little ones.

● Plan one of the best cruises for travel and vacation through the Eastern Mediterranean to soak up a perfect blend of history, architecture and breathtaking coastal scenery.

● Start planning your Mediterranean cruises here.

Turkey

Istanbul

Cruise to Turkey and depart at incomparable Istanbul, the city where Europe and Asia collide. Soak up the extraordinary atmosphere when admiring many traces from the Ottoman and Byzantine past. Join the locals during your Turkey vacation at one of the many lovely tea gardens, bars or restaurants. This is the kind of place you'll want to return to one day (soon).

Sultan Ahmed Mosque

The Sultan Ahmed Mosque has splendid domes, slender minarets and 260 windows. It's named after the sultan, who commissioned the mosque and reigned here from 1603 to 1617. While the mosque is grey on the outside, it's also called the Blue Mosque because of the blue tiles from the town of İznik that adorn the interior. Visitors can use the south door while worshippers use the main entrance.

Hagia Sophia

Situated beside the mosque is the no less impressive red colored Hagia Sophia, which was built as a Byzantine basilica in the 6th century. Back then, it was the world's largest building and an engineering marvel. It was also the world's largest cathedral for centuries until it became a mosque in the 15th century. In 1935, President Mustafa Kemal Atatürk decided to turn the mosque into a museum. Have a look at the glittering gold mosaics and learn more about this Turkish attraction’s fascinating history.

Trip to the Princes' Islands

Take a ferry across the Bosphorus to one of the Princes' Islands, nine islands southeast of Istanbul in the Sea of Marmara. The trip and a stroll around the islands will be one of the many highlights of your visit to Istanbul. The islands are mainly car-free and are a welcome change from the busy city streets. On the ferry, enjoy the views of mosques, palaces and timber mansions while sipping salep, a sweet, hot drink.

Grand Bazaar

Head to one of the world's largest covered bazaars to shop for spices, textiles and other gift-friendly souvenirs. The colorful market, a sprawling labyrinth in the heart of Istanbul's Old City, was established starting in 1455–56 by order of Mehmet the Conqueror. Take your time and drink tea with the vendors.

Topkapı Palace

Get a fascinating glimpse of life at the court of the Ottoman Empire, which was located here between the 15th and 19th centuries. Construction of the vast complex on a hill began in 1460, half a decade after the conquest of Constantinople. Walk around the gardens, the four courtyards and be amazed by the magnificent Imperial Hall (in the harem) and the sultan's Petition Room. Also impressive are the displays of sacred relics and precious jewels.

Ephesus (Kuşadası)

Travel to the resort town of Kuşadası on Turkey's Aegean coast. Great beaches, food and nightlife make this a popular destination and a good base for visiting Ephesus during your Turkey vacation. In Kuşadası, you can visit the recently renovated, picturesque Byzantine fortress and Kaleiçi Camii, the Old Town Mosque (built in the 17th century). You can also go shopping in the Grand Bazaar and the Orient Bazaar for treats and trinkets. Relax at the Kadınlar Denizi beach if you fancy a few hours of sun and sea. When translated, the name of this bay means “Ladies' Sea”.

Ephesus

The well-preserved ruins of Ephesus, a 1.5-square-mile area, give you an idea of life in the ancient Greco-Roman times. The UNESCO-listed World Heritage Site was built in the 10th century B.C. as a trading city and a center for the Anatolian fertility goddess Cybele. When the Roman Republic took control, it became a vibrant city of over 250,000 inhabitants. Excavations started 150 years ago, and still, only 29% of the ancient city has been uncovered.

Check out the Library of Celsus with its towering columns and the statue of the goddess of wisdom. The Scholastica Baths, with marble toilets and the remarkable Ephesus' Terraced Houses, are wildly fascinating as well.

Selçuk

Situated a few miles from Ephesus is the pleasant village of Selçuk. You can enjoy the views from the hilltop with the Byzantine ruins of the Basilica of St. John the Apostle, built in the sixth century, as well as the spectacular, well-preserved Ayasuluk Fortress.

Migrating storks use the nearby Roman and Byzantine Aqueduct for their huge nests. West of the center is a reconstructed pillar, which is what remains of the Temple of Artemis. This was once the biggest temple on Earth, and one of the Seven Wonders of the Ancient World.

Dilek Peninsula-Büyük Menderes National Park

Go hiking in this large mountainous national park south of Kuşadası. It’s located on a peninsula that is separated from the Greek island of Samos by a narrow strait. Admire the stunning vistas and deep-green forests, then take a dip in the azure blue sea from one of the sand or pebble beaches when you need to cool down. Don't be surprised if you spot a dolphin or some of the 256 bird species that live here.

Pamukkale

Consider a trip to the village of Pamukkale, 118 miles (190 km) east of Kuşadası. It’s famous for its surrealistic white terraces, called the "Cotton Castle" (pamuk means “cotton” in Turkish). A dip in the calcium-rich, blue thermal waters is an experience you won't easily forget. In the 2nd century B.C., people came to enjoy the healing waters, and the city of Hierapolis was built here. Visit the extensive ruins, such as the fountain, amphitheater and necropolis.

Greece

Santorini

Cruise to rocky, breathtaking Santorini — one of the best places to visit in Greece. As one of the Cyclades islands in the Aegean Sea, it's situated 120 miles (193 km) southeast of Greece's mainland. Officially called Thira, the island is known for its dramatic volcanic scenery and picturesque whitewashed villages. Its rugged landscape was formed by a volcanic eruption in the 16th century B.C.

Nea Kameni

Take a boat from the Fira or Athinios ports to the small, uninhabited island of Nea Kameni. It’s made of black lava rock and is almost round. You can hike the steep gravel paths to the top of the 427-feet-high (130 meters) volcanic crater and pass red, grassy succulents and active, smoking craters. Beside it is the even smaller Palea Kameni, which means “Old Burnt Island”, where you can relax at the sulfurous hot springs.

Whitewashed Towns

Santorini's principal towns, Fira and Oia, cling to cliffs. Stroll along the meandering streets and check out the photogenic white houses. The bustling capital of Fira can be reached by a cable car. Have a look at the picturesque blue-domed St. Gerasimos Church and the Byzantine castle ruins.

Next, sit down at a cozy waterfront taverna to enjoy Greek seafood. You'll have picturesque views of the sea, the other islands, the black and red lava pebbled beaches and Greece’s deep blue waters. In Oia, don't miss the stunning sunset and maybe even sample Santorini's delicious Vinsanto dessert wine.

Rhodes

When looking for ancient history combined with breathtaking nature and laid-back beaches, this is the right place. The Greek island of Rhodes, located less than 12 miles (19 km) from Turkey, was once famous for the Colossus, a 108-feet-high (33 meters) statue of the Greek sun-god Helios. Erected at the harbor in 280 B.C., it was considered one of the Seven Wonders of the Ancient World.

Nowadays, it's no surprise Rhodes is among the most visited of all Greek islands and a great spot for a Greece vacation.

The Medieval Old Town

The crusading Knights of St. John, a medieval Catholic military order, made Rhodes their stronghold from 1309 to 1522, leaving behind formidable fortifications and the Palace of the Grand Master.

They also left their traces on the gorgeous Old Town of Rhodes City, which is surrounded by medieval walls with seven gates and a dry moat bed. Climb the clock tower for a bird's-eye view of the city.

Palace of the Grand Master of the Knights of Rhodes

One of the highlights of the island is this medieval citadel, also known as the Kastello, and one of the few examples of Gothic architecture in Greece. Originally a Byzantine fortress, the Knights Hospitaller used it as their palace, headquarters and fortress. Admire the panoramic view from the high towers, and check out the pretty mosaic floors dating from Hellenic, Roman and early Christian times.

Acropolis of Lindos

Around 31 miles (50 km) south of Rhodes City, it's worth making the trip to the town of Lindos for its beautifully preserved, cliff-top acropolis. This natural citadel was fortified by the Greeks, the Romans, the Byzantines, the Knights of St. John and the Ottomans.

Stroll around the remains of the Temple to Athena Lindia, the monumental fourth-century gates and the columns of the Hellenistic stoa, once a covered walkway.

Israel

Jerusalem (Ashdod)

Cruise to Ashdod, the largest port in Israel, south of Tel Aviv, to start your Holy Land tours. From here, it's a one-hour drive east to the fabulous city of Jerusalem, or Al-Quds in Arabic, meaning "The Holy One." A visit to the city sacred to Jews, Muslims and Christians alike will be a memorable experience.

Pass through Damascus or Jaffa Gate, or one of the six other gates, and stroll around the mythical Old City, built in the early 16th century by the Turkish Sultan Suleiman the Magnificent.

Dome of the Rock Mosque

Head to the Temple Mount or Al Haram Ash Sharif, an ample public space sacred to all three Abrahamic faiths. You won't miss the iconic Dome of the Rock, constructed between 688 and 691, with its distinctive gold dome and traditional Islamic geometric designs. The dome covers a piece of stone sacred to both the Muslim and Jewish religions.

Next to the building is the Al-Aqsa Mosque, the third-holiest site in Islam. Non-Muslims are not permitted to enter the Dome of the Rock and Al-Aqsa Mosque. The Temple Mount plaza is surrounded by walls, including the Western Wall, Judaism's holiest prayer site.

Church of the Holy Sepulchre

Join the crowds of pilgrims through the Via Dolorosa street and follow the smell of frankincense to the intriguing Church of the Holy Sepulchre, one of Christianity's most sacred sites. The church was built in 335 A.D., destroyed in 1009 and then rebuilt. It’s believed this was where Jesus was crucified, died and was resurrected.

Yad Vashem Memorial

Yad Vashem means "A Memorial and a Name." This is Israel's official memorial to the six million Jews who were killed during World War II. The 18-hectare site honors the people who died, with a research center to record the names of people who didn't have any family. There are photos of the victims and an eternal flame near a crypt containing their ashes.

Haifa

Cruise to Haifa, the country's third-largest city, which is beautifully set on the slopes of Mount Carmel. You'll find several interesting sights and a pleasant, sandy beach to enjoy during your Holy Land tours. Stroll around Wadi Salib, the Old City center near the port, and continue to Wadi Nisnas, the Arab quarter.

The trendy German Colony neighborhood is not to be missed either. Still, the absolute highlight is the iconic Shrine of the Bab.

Bah'ai World Center

Haifa is the world center for the Baha'i faith. You can walk around the lovely Bah'ai Gardens set around the 19 steep terraces. Next, visit the Shrine of the Bab, a UNESCO World Heritage site. The striking golden dome is composed of 12,000 tiles. Men and women must be covered from the shoulders to the knees.

The pilgrimage site, built in 1953, is said to hold the remains of the Bab. The free, 45-minute Panorama Tour is highly recommended. From the Viewing Balcony, you’ll appreciate a breathtaking view of the shrine out toward the Mediterranean Sea.

German Colony

At the foot of the Baha'i Gardens is this picturesque, restored neighborhood. It was founded in the late 1860s by German Templars, who came to establish a Christian community here. Experience the lively culture near the tourism center and take a moment to admire the pretty stone houses amongst the attractive cafés, restaurants, art galleries and boutiques.

Stella Maris Carmelite Monastery

For magnificent views of Haifa and the surroundings, take the cable car at Bat Galim's seafront promenade up to Mt. Carmel. Visit the Stella Maris Carmelite Monastery and the church with its beautifully painted ceiling and dome. The monastery — Latin for "Star of the Sea" — was established in the late 12th century. The current building was constructed in 1836. Remember to wear clothing that covers your shoulders and knees as a sign of respect.

Royal Caribbean Eastern Mediterranean Cruise Ports

● Santorini.

● Rhodes.

● Istanbul.

● Ephesus.

Cruise to the Eastern Mediterranean for a Culture-Inspired Vacation

From the bustling bazaars of Istanbul to the sun-drenched cliffs of Santorini, and from the ancient ruins of Ephesus to Jerusalem’s sacred sites, the Eastern Mediterranean offers a stunning tapestry of history, culture and natural beauty.

Each destination reveals its own story, from Ottoman palaces and Byzantine wonders to volcanic islands and UNESCO treasures. You could be wandering cobblestone streets, sampling local cuisine or marveling at iconic landmarks — every stop promises unforgettable experiences.

Start your journey today! Plan a cruise through these remarkable locations and immerse yourself in the magic of a true Mediterranean tour.

Explore Royal Caribbean Eastern Mediterranean cruises today.